BioNOC™ II are carriers for the growth of animal, mammalian and insect cells. Most anchorage-dependent cells have been successfully grown in BioNOC™ II carriers in both serum-containing and serum-free medium.

BioNOC™ II is made of 100% pure polyester non-woven fabrics according to cGMP guidelines.

The fabric is specially surface-treated to make it hydrophilic and biocompatible. It is then processed through a cutting procedure to form 5mm wide and 10mm long strips.

Features:

Pure:
· 100% pure PET non-woven fabrics; regulation friendly
· Non-pyrogenic
· Non-cytotoxic
Light:
· High cell density (up to 1x109 cells/g)
High S/V:
· High surface area to volume ratio; S/V = 300 cm-1
· High specific surface area (2,400 cm2/g)
Consistent:
· Novel surface treatment technology with no decay of hydrophilicity
· All materials are manufactured according to cGMP guidelines

Specifications:

Material: 100% PET
Dimension: 5mm x 10mm Strip
Porosity: ~94% in Packed Bed
Specific Surface Area: 2,400cm?/g
Packed Volume: 15ml/g
Autoclavable: (121°C, 30 min. in PBS)
Gamma Irradiation: (25kGy)
Endotoxin Tested (Limulus Ameobocyte Lysate): (<0.25 EU/ml)
BioBurden: (<1 CFUig)
Cytotoxicity Tested: (Serum and Serum-Free Culture Test)
Quality Control: Bioburden, LAL Test, Cytotoxicity, Growth Performance According to USP <87><88>, ISO 10993-5